--- src/Makevars.in	2023-10-25 02:13:48.000000000 +0800
+++ src/Makevars.in	2023-10-27 04:21:49.000000000 +0800
@@ -6,5 +6,5 @@
 #      endif
 #endif 
 
-PKG_CPPFLAGS = -I/usr/include/openbabel3  -I/usr/include/eigen3  -DUSE_BOOST -DHAVE_EIGEN  -I/usr/local/include/eigen3 -I/usr/local/include/openbabel3  @OPENBABEL_CFLAGS@ 
-PKG_LIBS =  -L/usr/local/lib/openbabel3  @OPENBABEL_LIBS@
+PKG_CPPFLAGS = @PKG_CPPFLAGS@
+PKG_LIBS = @PKG_LIBS@