Do not override the MacPorts install_name defaults. --- cmake/macros.cmake.orig 2018-03-27 07:17:46.000000000 -0500 +++ cmake/macros.cmake 2018-03-27 07:37:39.000000000 -0500 @@ -70,10 +70,6 @@ RUNTIME DESTINATION ${LASZIP_BIN_INSTALL_DIR} LIBRARY DESTINATION ${LASZIP_LIB_INSTALL_DIR} ARCHIVE DESTINATION ${LASZIP_LIB_INSTALL_DIR}) - if (APPLE) - set_target_properties(${_name} PROPERTIES INSTALL_NAME_DIR - "@executable_path/../lib") - endif() endmacro(LASZIP_ADD_LIBRARY) ###############################################################################